The South Sydney Rabbitohs host the Penrith Panthers in a clash at Accor Stadium.
In a late change Lindsay Smith will start for the Panthers, with Moses Leota coming off the bench.
Ben Hornby has rung in the changes since taking over as interim coach following the sacking of Jason Demetriou.
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Hornby has wasted no time in leaving his imprint on the side making mass changes from the team named on Tuesday afternoon.
Jacob Gagai drops out with Isaiah Tass moving to the wing, while Michael Chee Kam shifts from the second row to the centres.
Jai Arrow start at prop with Keaon Koloamatangi shifting to the second row and Sean Keppie is the new man on the bench.
For the Panthers Nathan Cleary has been rested due to his nagging hamstring injuries and the short turnaround form the Cowboys clash with Brad Schneider back at halfback.
Jack Cole comes onto the bench for Daine Laurie in a tweak to the interchange rotation.
TEAMS
Rabbitohs team: 1. Jye Gray 4. Isaiah Tass 3. Jack Wighton 11. Michael Chee Kam 5. Izaac Tu’itupou Thompson 6. Cody Walker 7. Dean Hawkins 17. Jai Arrow 9. Damien Cook 10. Davvy Moale 8. Keaon Koloamatangi 12. Jacob Host 13. Cameron Murray 14. Peter Mamouzelos 15. Siliva Havili 16. Thomas Burgess 19. Sean Keppie. 18th man: 18. Tallis Duncan
Panthers team: 1. Dylan Edwards 2. Sunia Turuva 3. Izack Tago 4. Taylan May 5. Brian To’o 6. Jarome Luai 20. Brad Schneider 15. Lindsay Smith 9. Mitch Kenny 10. James Fisher-Harris 11. Luke Garner 12. Liam Martin 13. Isaah Yeo 8. Moses Leota 16. Matt Eisenhuth 17. Mavrik Geyer 18. Jack Cole. 18th man: 22. Tyrone Peachey
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Source Agencies